Oral finasteride and topical finasteride are both effective treatments for hair loss, but they differ in their mechanisms, absorption, and side effects.
Effectiveness
- Oral Finasteride:
- Well-established treatment for androgenetic alopecia.
- It inhibits the enzyme 5-alpha-reductase, reducing DHT levels.
- Approximately 80% of men experience hair regrowth or stabilization.
- Topical Finasteride:
- Emerging evidence suggests comparable effectiveness to oral finasteride.
- Achieves significant reduction in scalp DHT levels (68-75%).
- Promising results in increasing hair counts and density.
Side Effects
- Oral Finasteride:
- Potential systemic side effects, including sexual dysfunction (less than 4% of users).
- Side effects occur due to systemic circulation of the drug.
- Topical Finasteride:
- Minimizes systemic exposure, reducing the likelihood of side effects.
- Lower absorption rates (10-15 times less than oral form).
- Mild local side effects (e.g., skin irritation) may occur.
Conclusion
- Both forms are effective for hair loss treatment.
- Topical finasteride may offer similar benefits with reduced risk of systemic side effects.
- The choice depends on personal preference regarding convenience and tolerance for potential side effects.
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